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Please use this identifier to cite this item:
http://hdl.handle.net/2142/5160
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| Title: |
Fractional derivative models and their use in the characterization of hydropolymer and in-vivo breast tissue viscoelasticity |
| Authors: |
Coussot, Cecile |
| Keywords: |
Fractional derivative models
Viscoelasticity |
| Issue Date: |
2008-Apr-20 |
| Abstract / Summary: |
The Viscoelastic response of hydropolymers, which include gelatin phantom and glandular breast
tissue, may be accurately characterized with as few as three parameters using the Kelvin-Voigt Fractional
Derivative (KVFD) modeling approach. We propose to image these parameters for simulated
and experimental imaging phantoms and to estimate them for normal and cancerous in-vivo breast
tissues. After a detailed presentation of the processing algorithm and discussion of its performances,
we analyze the KVFD parameter values in simulated and experimental hydrogels. We show that the
KVFD parameters can separate the biphasic mechanical properties of hydropolymers that describe
the response of its solid and fluidic components and present the effects of pH and concentration
changes in gelatin phantoms. We then interpret average results observed in normal and cancerous
breast tissues and show that this modeling approach may be applied to tumor differentiation. |
| URI: |
http://hdl.handle.net/2142/5160 |
| Type of Resource: |
text |
| Genre of Resource: |
dissertation/thesis |
| Publication Status: |
unpublished |
| Peer-Reviewed: |
not peer reviewed |
| Appears in Collections: |
UIUC Master Theses
Bioengineering Masters Theses
UIUC Research and Scholarship (Uncategorized)
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Thesis040908.pdf (4Mb)
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Master's thesis |
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